Use of NSAID"s May Inhibit Bone Healing

Newsdate: Fri, 25 Feb 2011 - 12:59 pm
Location: LEXINGTON, Kentucky

Edited News Release

Nonsteroidal anti-inflammatory drugs (NSAIDs) such as phenylbutazone and flunixin meglumine are used to reduce inflammation and pain from injuries, surgery, or bone fractures. New research has discovered that NSAIDs have the potential to inhibit bone healing, especially in the early stages.

Higher doses and longer periods of use were linked to increased inhibition of bone healing in studies with rabbits and rodents. In the single study involving horses, biopsies were taken from the bones of horses receiving phenylbutazone and from a control group not receiving the medication. At 16 and 30 days, there was less mineralized tissue in the biopsy sites in horses that had received phenylbutazone.

Though the difference in mineralization was minor, it could be important in how quickly and strongly bones repair themselves. Horse owners are advised to consult a veterinarian on the use of phenylbutazone or other NSAIDs to relieve discomfort for any injury.

About the author

As an animal lover since childhood, Flossie was delighted when Mark, the CEO and developer of EquiMed asked her to join his team of contributors.

She enrolled in My Horse University at Michigan State and completed a number of courses in everything related to horse health, nutrition, diseases and conditions, medications, hoof and dental care, barn safety, and first aid.

Staying  up-to-date on the latest developments in horse care and equine health is now a habit, and she enjoys sharing a wealth of information with horse owners everywhere..

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