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Ranitidine

Pronunciation

ran-IT-ih-deen - Pronunciation guide

Brand Names

Description

Ranitidine is an ulcer medication effective in both people and horses. As an H-2 blocker, it reduces acid production.

Usage

Ranitidine is used to treat gastro-duodenal ulcers in horses. The first step in treatment of ulcers in horses is the removal of stressful conditions and discontinuation of any anti-inflammatory medications. Veterinarians often recommend a combination of medications and a treatment period of at least three to four weeks.

Dosage and Administration

Method Amount Dosage Period Duration Note
Oral 3 mg/lb 3 times a day As prescribed Dose form: Tables: 75 mg, 150 mg, and 300 mg
IV 0.7 mg/lb 3 times a day As prescribed Dose Form: Injectable: 25 mg/ml

Side Effects

Ranitidine has been shown to have a wide margin of safety in laboratory animals.

Precautions

Ranitidine should be used with caution or at a reduced dose in horses with liver or kidney problems.

Ranitidine is not FDA approved for use with horses, but is commonly used and considered accepted practice. U. S. federal law restricts these drugs to use by or on the lawful written or oral order of a licensed veterinarian.

Ranitidine is forbidden in any drug-free competition. It is important to check with a knowledgeable veterinarian and the individual regulatory group.

Interactions

Histamine H2 receptor antagonists may affect blood clotting in animals on warfarin.

Some veterinarians recommend separating oral doses of ranitidine from antacids, metoclopramide, and sucralfate.

Overdose

No information was found regarding overdose of ranitidine in horses or other animals.

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