soo-doe-eh-FED-reen, pye-RIL-uh-meen MA-le-ate - Pronunciation guide
- Tri-Hist Granules
Pseudoephedrine HCI USP and Pyrilamine Maleate USP are combined in equal measures, usually 600 mg each, in a palatable corn meal base for use in horses when an antihistamine decongestant is needed.
The pseudoephedrine HCI USP acts as a decongestant and Pyrilamine Maleate USP acts as an anti-histamine.
Histamines are substances released from some types of cells when the cells become damaged. Histamines cause inflammation, swelling and itching. Antihistamines compete with histamine for uptake at the histamine receptors on sensitive cells in the respiratory tract, intestines, blood vessels and skin.
Tri-Hist Granules is the brand name of a pseudoephedrine and pyrilamine maleate combination that acts as a bronchodilator and is used as a histamine antagonizing preparation in treating allergic problems in horses such as hives, swelling due to bee stings, insect bites or contact with an irritating substance.
Dosage and Administration
|Pseudoephedrine and Pyralimine Maleate|
(click row for calculator)
|Oral (granules)||0.5 ounce/1000lbs||Every 12 hours as needed||NA|
Sedation is the most common side effect, although excitement, fine tremors, colic and loss of appetite are possible.
Do not use at least 72 hours before sporting events.
Not for use in horses intended for human consumption.
Tri-Hist Granules are FDA approved for use in horses. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Check with the appropriate individual regulatory group regarding use in competition horses.
Antihistamines have an additive effect when combined with other central nervous system depressant drugs such as tranquilizers.
Antihistamines may affect the activity of anticoagulants such as warfarin.
Quinidine Sulfate Tablets