2015 Nobel Prize Winners Laid Groundwork for Animal-Health Breakthroughs Including Parasite Control in Horses

Newsdate: Tue 10 November 2015 – 10:16 am
Location: DULUTH, Georgia

Dr. William C. Campbell and Dr. Satoshi Omura were awarded the prestigious 2015 Nobel Prize for Medicine for their discovery of avermectin. The active ingredient that revolutionized the animal-health industry and also led to the treatment of some of the most devastating parasitic diseases, including river blindness in humans. It also prevents heartworm disease in dogs.1

Discovery of Avermectin as parasite control in horses

Discovery of Avermectin as parasite control in horses

Dr. William C. Campbell and Dr. Satoshi Omura were awarded the prestigious 2015 Nobel Prize for Medicine for their discovery of avermectin which revolutionized the animal-health industry and led to the treatment of devastating parasitic diseases, including several dewormers for horses.

Originally developed for livestock, the ground-breaking discovery of avermectin led to the development of Merial products that have had a significant impact on the international food supply today.

Building on Campbell and Omura’s heritage, scientists at Merial created IVOMEC® (ivermectin), the first endectocide for both internal and external parasites in cattle. IVOMEC uses a modified version of avermectin called ivermectin.

This advancement revolutionized the parasite control category, providing an opportunity to safely increase production of an important source of high-quality protein for a growing worldwide population. Another tribute to this molecule’s innovation is its amazing effectiveness even today after decades of use.

“In 1984 when IVOMEC was launched in the U.S., it was truly a game changer due to its unique broad spectrum, efficacy and safety. The animal health industry had never seen anything like it. The product is administered at such a low dose rate, researchers had to develop new methods to measure it. This was a brand new concept for pharmaceutical companies,” says Bruce Nosky, DVM, director of Merial Large Animal Veterinary Services.

Merial also was able to utilize ivermectin outside of its livestock division. Merial scientists created products such as HEARTGARD® Plus (ivermectin/pyrantel), the most recommended heartworm disease preventive for dogs2, and ZIMECTERIN® Gold (ivermectin/praziquantel), one of several dewormers for horses.

Later, EPRINEX® (eprinomectin), formulated with the avermectin-based molecule eprinomectin, was created with unique properties such as being weatherproof and including a zero milk withdrawal time on the label.

Most recently, Merial scientists created a new product, LONGRANGE® (eprinomectin), that allows control of parasites in cattle for up to 150 days in a single dose3 – and that’s something conventional dewormers just can’t match.4-6 Because of its innovation and contribution to the animal health industry, it was recognized by Animal Pharm as Best Food Animal Product 2014.

“Merial is a leader in parasite -control products for the pet, cattle and equine industries – in large part because of the efforts of these scientists,” said Nosky. “We extend our congratulations and thanks to these extraordinary scientists, and are proud to be part of their legacy.”

Much like Dr. Campbell and Dr. Omura, Merial is dedicated to continually provide new technologies to help move the animal-health industry forward. Today, Merial markets a variety of products with avermectin as the parent to the active ingredient. To learn more about these products offered and about Merial, visit http://www.merial.com.

About Merial
Merial is a world-leading, innovation-driven animal health company, providing a comprehensive range of products to enhance the health and well-being of a wide range of animals. Merial employs 6,100 people and operates in more than 150 countries worldwide with more than €2 billion of sales in 2014. Merial is a Sanofi company. For more information, please see www.merial.com
®IVOMEC, EPRINEX, LONGRANGE, HEARTGARD and ZIMECTERIN are registered trademarks of Merial. ©2015 Merial, Inc., Duluth, GA. All rights reserved. RUMIEIP1501 (10/15)
1 World Health Organization. WHO welcomes Nobel Prize in Physiology or Medicine 2015 for discoveries of drugs against tropical diseases. http://www.who.int/neglected_diseases/news/nobel_prize_2015/en/. Accessed October 6, 2015.
2 Data on file at Merial: Veterinarian’s #1 choice for heartworm disease prevention in dogs.
3 Dependent upon parasite species, as referenced in FOI summary and LONGRANGE product label.
4 CYDECTIN Injectable product label.
5 DECTOMAX Injectable product label.
6 SAFE-GUARD product label.

About the Author

Flossie Sellers

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As an animal lover since childhood, Flossie was delighted when Mark, the CEO and developer of EquiMed asked her to join his team of contributors.

She enrolled in My Horse University at Michigan State and completed a number of courses in everything related to horse health, nutrition, diseases and conditions, medications, hoof and dental care, barn safety, and first aid.

Staying up-to-date on the latest developments in horse care and equine health is now a habit, and she enjoys sharing a wealth of information with horse owners everywhere.

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