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Nitrofurazone

Pronunciation

ni-tro-FYOOR-uh-zone - Pronunciation guide

Brand Names

  • Cooper's Best MFZ Equine Dressing
  • Fura-Septin
  • Fura-Zone
  • NFZ Wound Dressing
  • Nitrofurazone Ointment
  • Nitrofurazone Soluble Dressing

Description

Nitrofurazone is the active antibacterial ingredient in a water-soluble base of polyethylene glycols used in the prevention or treatment of surface bacterial infections of wounds, burns, and cutaneous ulcers.

Usage

Nitrofurazone is used to prevent or treat surface bacterial infections of wounds, burns, and cutaneous ulcers. It is also used to treat urinary tract infections and metritis.

Nitrofurazone is also combined with other medications, such as Neomycin sulfate, prednisolone, and chlorophyll for treatment of bacterial and mycotic infections, eczema, infected wounds and burns, post-operative dressing, irritation, edema, and greasy heel.

Dosage and Administration

For prevention or treatment of surface bacterial infections of wounds, burns, and cutaneous ulcers

Method Amount Dosage Period Duration Note
Topical Thin coat   Treatment Duration Apply the ointment directly on the wound or lesion with a spatula or place it on a piece of gauze to be used as a bandage. The preparation should be in contact with the wound or lesion for at least 24 hours. The dressing may be changed several times or left on for a longer period as directed by a veterinarian.

For urinary tract infections

Method Amount Dosage Period Duration Note
Oral 2.5 - 4.5 mg/kg Every 8 hours As prescribed  

Side Effects

Redness, swelling, or signs of irritation may occur, in which case, discontinue use and consult a veterinarian.

Precautions

Nitrofurazone has been shown to produce mammary tumors in rats and ovarian tumors in mice. Some people may be hypersensitive to this product. Wear gloves or wash hands thoroughly after use.

Nitrofurazone is FDA-approved for use in horses. It is a prescription drug and U. S. federal law restricts this drug to use by or on the lawful written or oral order of a licensed veterinarian.

Nitrofurazone would be prohibited in any drug-free competition. Check with the proper regulatory group.

Interactions

None noted in literature.

Overdose

No information is available.

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Literature

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