Imidocarb Dipropionate

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IM-i-doh-carb die-PRO-pee-oh-nate - Pronunciation guide

Brand Names

  • Imizol


Rx symbol Imidocarb Dipropionate is an Anti-protozoal drug. Protozoa are single-cell animals that can easily be seen with a microscope. These animals, amongst which are the common amoeba, are responsible for many gastrointestinal and circulatory ailments.


Imidocarb dipropionate is used in the treatment and control of rickettsial diseases including Babesiosis (piroplasmosis) in the horse.  Treatment protocol using Imidocarb Dipropionate was developed to clear the horse of the infectious stages of Babesia caballi and Theileria equi.

Dosage and Administration

Prescription medicationImidocarb dipropionate
Method Dosage
(click row for calculator)
Concentration Period Duration
Intramuscular injection 4 mg/kg 120 mg/ml Every 72 hrs 4 doses


  • Federal law restricts this drug to use by or on the order of a licensed veterinarian..
  • Equine piroplasmosis is classified as a reportable disease in the United States.  Treatment may only be undertaken under proper federal supervision.
  • Imizol is labeled for use in dogs; use in horses constitutes an extra-label drug use and may only be undertaken under the direction of a licensed veterinarian.
  • Imidocarb has significant toxic side-effects and should not be used in the horse except by a veterinarian to treat piroplasmosis.
  • Calculator is for educational purposes only. Follow your veterinarian's instructions regarding use of this, or any medication.

Side Effects

Pain during injection; injection site reactions; colic; diarrhea; excessive tearing; sweating; nasal discharge


Do not administer to patients exposed to cholinesterase-inhibiting drugs, pesticides, or chemicals.  Some side-effects may be mitigated by pre-medication with anti-inflammatory drugs.  Donkeys may be sensitive to the toxic effects of the drug.  Do not administer intravenously


None except as noted in the precautions.


Toxicity signs are similar to the listed side-effects.  Chronic toxicity may damage liver, intestine, and lungs.


Imidocarb Dipropionate for Injection



Dig deeperTM

Re-Emergence of the Apicomplexan Theileria equi in the United States: Elimination of Persistent Infection and Transmission Risk 

Babesiosis (Piroplasmosis)

New Effective Treatment for Horses with Piroplasmosis


About the Author

EquiMed Staff

EquiMed staff writers team up to provide articles that require periodic updates based on evolving methods of equine healthcare. Compendia articles, core healthcare topics and more are written and updated as a group effort. Our review process includes an important veterinarian review, helping to assure the content is consistent with the latest understanding from a medical professional.