N-Butyl Scopolammonium Bromide

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n-BYOO-tyl SKOP-ol-am-mon-i-um BRO-mide - Pronunciation guide

Brand Names

  • Buscopan Injectable Solution


Rx symbolN-butylscopolammonium bromide has been used for many years in Europe as a first line of treatment for minor gas colic in horses. It is a water-soluble, white crystalline substance that is the main ingredient in Buscopan. As a short-acting antispasmodic with no sedative properties, it is unlikely to mask more serious medical or surgical emergencies.


N-butylscopolammonium bromide is used to treat minor gas colic in horses. It is also used by some veterinarians to treat esophageal obstruction or "choke" because of it's ability to relax the smooth muscle of the esophagus.

N-butylscopolammonium bromide has been found to be effective for relaxing the rectum and decreasing rectal straining, making rectal examination less difficult or risky for the animal.

Dosage and Administration

Prescription medicationN-Butyl Scopolammonium Bromide
Method Dosage
(click row for calculator)
Concentration Period Duration
Slow Intravenous injection 0.3 mg/kg 20 mg/ml Episode NA


  • Federal law restricts this drug to use by or on the order of a licensed veterinarian.
  • Extra-label use of drugs in treating animals is allowable only by licensed veterinarians within the context of a valid veterinarian-client-patient relationship, and does not include drug use in treating animals by the layman (except under the supervision of a licensed veterinarian).
  • Calculator is for educational purposes only. Follow your veterinarian's instructions regarding use of this, or any medication.

Side Effects

N-butylscopolammonium bromide will cause temporary increase in heart rate for approximately 30 minutes. It may also cause temporary dilation of the pupils of the eyes.


N-butylscopolammonium bromide should not be used when abdominal pain, accompanied by lack of gastrointestinal activity, is present. Some veterinarians use heart rate as a tentative indicator of pain severity. When this drug is being administered, approximately 30 minutes should elapse before heart rate is used as an indication of the horse's discomfort.

N-butylscopolammonium bromide is FDA-approved for use with horses. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

N-butylscopolammonium bromide is a prohibited substance in most sanctioned competitions. It is important to check with the individual regulatory group.


The effects of N-butylscopolammonium bromide may increase when used with other anticholinergic drugs, used to inhibit the parasympathetic nerve impulses responsible for involuntary movement of small muscles in the gastrointestinal tract.


Overdose causes an increase in duration and severity of side effects and may cause mild colic.


Buscopan Injectable N-Butyl Scopolammonium BromideBuscopan Injectable N-Butyl Scopolammonium Bromide



About the Author

EquiMed Staff

EquiMed staff writers team up to provide articles that require periodic updates based on evolving methods of equine healthcare. Compendia articles, core healthcare topics and more are written and updated as a group effort. Our review process includes an important veterinarian review, helping to assure the content is consistent with the latest understanding from a medical professional.