A recent study published in the Journal of the American College of Nutrition showed that a popular dietary supplement which was tested in horses had no adverse effects and is suitable for use in both horses and humans.
A dietary supplement for active horses and humans
This study shows that long-term ingestion of d-Ribose has no ill effects on racehorses and, in addition, d-Ribose supplementation protected the horses from cramping while enhancing muscle recovery at the same time.
d-Ribose is a popular dietary supplement for humans and equines because of its crucial role in cellular bioenergetics. However, as a reducing sugar, it has been suggested that ingestion of d-ribose might promote the formation of glycated proteins in vivo with potential adverse consequences.
The aim of this study was to examine if Ribose would promote the formation of glycated proteins in vivo following exercise in training thoroughbred racehorses.
The study was carried out with 2-year-old healthy thoroughbred racehorses at the Berkley Farm in Darlington, Maryland. Two groups of 5 horses each were used in the study. The weight of the horses ranged from 520 to 570 kg with a mean of 545 kg.
The two groups of horses received the supplement (30 and 50 g d-Ribose daily) for 17 weeks, during which period the horses were subjected to low-intensity exercises followed by high-intensity exercises. Blood samples were analyzed for glycated plasma proteins at baseline and following the 2 exercise regimens.
This study shows that long-term ingestion of d-Ribose at 30-50 g a day does not promote the formation of glycated plasma proteins in thoroughbred racehorses.
In addition, Ribose supplementation also protected the horses from cramping while enhancing muscle recovery at the same time. No adverse effects were reported.
Ribose supplementation is safe and does not cause glycation in vivo. This investigation also establishes safety of Ribose in thoroughbred racehorses, suggesting similar implications in humans as well.