Third 2023 Case of West Nile Virus Confirmed in California Horse

Veterinarian vaccinating a horse.
Veterinarian vaccinating a horse. Karin Belgrave

Newsdate: Thursday, August 10, 2023 - 11:30 am
Location: SACRAMENTO, California

The third case of West Nile Virus in California in 2023 has been confirmed in Fresno County. On August 8, 2023, a 7-year-old Quarter Horse gelding with unknown vaccine history in Fresno County displaying neurologic signs was confirmed positive for West Nile Virus. The gelding is alive and recovering.

Visiting veterinarian ready to vaccinate horses in pasture.

Visiting veterinarian ready to vaccinate horses in pasture.

Mosquitos feeding on infected horses have not demonstrated the ability to ingest enough virus to transmit it to other animals or humans so horses and humans are considered dead end hosts.
© 2020 by OIE Bulletin-John Grewar

The second case of West Nile Virus in California in 2023 was confirmed in Kings County. On July 31, 2023, a 4-year-old vaccinated Quarter Horse mare in Kings County displaying neurologic signs was confirmed positive for West Nile Virus. The mare is alive and recovering.

The first case of West Nile Virus in California in 2023 was confirmed in Kern County. On July 10, 2023, a 6-year-old vaccinated Warlander mare in Kern County displaying neurologic signs was confirmed positive for West Nile Virus. The mare is alive and recovering. For 2023 so far, a total of three (3) horses have been confirmed positive for WNV in California. 

The positive horses were located in Kern County (1), King County (1), and Fresno County (1). No horses were unvaccinated, one (1) horse had unknown vaccine history, and two (2) were vaccinated. Three (3) horses are alive and/or recovering, and no horses were euthanized/died. 

CDFA urges horse owners to consult their veterinarian concerning a WNV vaccination program to ensure maximum protection of their horses.West Nile Virus West Nile Virus (WNV) is a mosquito-borne virus first detected in the United States (U.S.) in the New York City area in 1999. Since 1999, the virus has spread throughout the U.S. and Canada, infecting birds, humans, horses, and other animals.

As of 2015, more than 27,000 horses in the U.S. have been infected since the disease was first identified. The virus is maintained in the wild bird population and is spread between birds by mosquitos. Birds are considered the natural reservoir for WNV since high levels of virus circulate in their bloodstream. Mosquitos acquire WNV in blood meals from infected birds and pass it on to other birds, animals, and people.

Mosquitos that feed on an infected horse or human have not demonstrated the ability to ingest enough of the virus to transmit it to other animals or humans; therefore, horses and humans are considered “dead end hosts.” Clinical Signs West Nile Virus may cause a wide range of clinical illness ranging from mild” flu-like” signs to encephalitis (inflammation of the brain) that may be fatal to both humans and horses.

While horses are susceptible to WNV infection, many infected horses do not develop clinical illness and recover uneventfully.

Consult a veterinarian if your horse exhibits any of the following clinical signs:

  • Fever
  • Incoordination, especially in rear limbs, causing stumbling and falling
  • Generalized weakness, muscle twitching, seizures or coma
  • Drooping lips and lip smacking, head drooping, grinding teeth
  • Hypersensitivity to touch or sound
  • Recumbency (inability to rise)

Diagnosis

Any horse displaying abnormal behavior or neurologic signs should be examined by a veterinarian to rule out neurologic diseases, such as WNV, Equine Herpes Virus-1, Equine Protozoal Myeloencephalopathy, Eastern/Western Encephalomyelitis and Rabies. 



Blood samples should be collected by a veterinarian and sent for diagnostic testing. The WNV IgM capture ELISA test is a specific test that detects acute WNV infection in animals, is usually positive within six (6) days post infection and can remain positive for up to two (2) months post infection. A positive WNV IgM Capture ELISA test is indicative of recent infection.

Unexposed animals vaccinated for WNV will test negative on the WNV IgM capture ELISA test. Treatment and Prognosis Currently, there is no specific treatment for WNV. Supportive care includes administration of anti-inflammatory drugs and intravenous fluids.

Recumbent WNV positive horses are at a higher risk of dying or requiring euthanasia. For horses exhibiting clinical signs of WNV, the case fatality rate is approximately 33%; however, many infected horses will fully recover following infection.

Prevention

Vaccination and mosquito control minimize the risk of WNV infection in horses. Although the number of WNV infected horses has declined over the last five years, WNV remains an important disease in unvaccinated horses. The American Association of Equine Practitioners (AAEP) recommends incorporation of a WNV vaccine as an annual core vaccine in equine vaccination protocols.

Currently, there are four United States Department of Agriculture (USDA)-licensed WNV vaccines available for horses in the U.S. Horse owners should consult with their veterinary practitioner to ensure current WNV vaccination status of their horses.

Mosquito Control Minimizing horse exposure to mosquitoes during the peak mosquito feeding periods at dawn and dusk decreases the risk of horse exposure to WNV. Application of mosquito repellant can also effectively reduce the number of mosquito bites on horses. Mosquito control efforts to eliminate mosquito breeding sites are also important.

Methods to eliminate mosquito breeding sites include:

  • Draining unnecessary standing water found in wheelbarrows, tires, etc.
  • Cleaning water containers at least weekly (i.e., bird baths, plant saucers)
  • Scheduling pasture irrigation to minimize standing water
  • Keeping swimming pools optimally chlorinated and draining water from pool covers
  • Stocking of water tanks with fish that consume mosquito larvae (Contact local mosquito control for assistance) or use mosquito “dunk” available at hardware stores.

Press release by CDFA Animal Health and Food Safety Services, Animal Health Branch

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