Description

Fenbendazole is a broad spectrum anthelmintic that is used to control a number of common equine parasites, including large strongyles (Strongylus edentatus, S. equinus, S. vulgaris), encysted early third stage (hypobiotic), late third stage and fourth stage cyathostome larvae, small strongyles, pinworms (Oxyuris equi), ascarids (Parascaris equorum), and arteritis caused by fourth stage larvae of Strongylus vulgaris.

While not completely understood, the antiparasitic action of Fenbendazole is believed to result from the inhibition of energy metabolism of the parasite.

Usage

Fenbendazole is used as a part of a veterinary reviewed and approved program of parasite control. This program may include a multi-dose regime over a period of days specifically to control of the migrating larvae of S. vulgaris.

Dosage and Administration

Side Effects

In horses, no side effects for a single dosage as high as 454 mg/lb were noted. Mutliple doses of 22.7 mg/lb were also administered on 15 consecutive days without side effects. In rare cases, antigens produced by the dying parasites may result in either a local or systemic hypersensitive reaction.

Precautions

Panacur® (fenbendazole) Paste 10% has been evaluated for safety in pregnant mares during all stages of gestation with doses as high as 11.4 mg/lb (25 mg/kg) and in stallions with doses as high as 11.4 mg/lb (25 mg/kg). No adverse effects on reproductivity were detected.

The recommended dose for control of fourth stage larvae of Strongylus vulgaris, 4.6 mg/lb (10 mg/kg) daily for 5 consecutive days, has not been evaluated for safety in stallions or pregnant mares.

Interactions

No interactions with other drugs or medications is noted.

Overdose

Immediately consult with a veterinarian if overdosing occurs.